Sex Differences in Aortic Valve Calcification

Sex differences in aortic valve calcification.

Sex differences in aortic valve calcification measured by multidetector computed tomography in aortic stenosis.

BACKGROUND Aortic valve calcification (AVC) is the intrinsic mechanism of valvular obstruction leading to aortic stenosis (AS) and is measurable by multidetector computed tomography. The link between sex and AS is controversial and that with AVC is unknown. METHODS AND RESULTS We prospectively performed multidetector computed tomography in 665 patients with AS (aortic valve area, 1.05±0.35 cm...

Human aortic valve calcification.

To the Editor: Rajamannan et al1 addressed the problem of bone formation in calcified aortic valves, quoting the publication of actual bone formation by Mohler et al.2 Mohler et al had indicated that ossification in calcified aortic valves was relatively common, finding evidence of valve ossification in 36 of 323 patients. Of historical interest, I reported ossification in the left ventricular ...

Effect of immunological differences on rat aortic valve allograft calcification.

Calcification may be a cause of allograft valve degeneration. To determine whether immunological differences between donor and recipient affect the degree of calcification that occurs, adult Lewis rats received aortic valve allografts transplanted heterotopically into the abdominal aorta. All valves were transplanted immediately after harvest. The valves were not exposed to antibiotics or album...

Aortic valve calcification in mild primary hyperparathyroidism.

CONTEXT It is unclear whether cardiovascular disease is present in primary hyperparathyroidism (PHPT). OBJECTIVE Aortic valve structure and function were compared in PHPT patients and population-based controls. DESIGN This is a case-control study. SETTING The study was conducted in a university hospital metabolic bone disease unit. PARTICIPANTS We studied 51 patients with PHPT and 49 co...